Package: adpss Title: Design and Analysis of Locally or Globally Efficient Adaptive Designs Version: 0.1.2 Authors@R: person("Kosuke", "Kashiwabara", email = "kashiwabara-tky@umin.ac.jp", role = c("aut", "cre")) Description: Provides the functions for planning and conducting a clinical trial with adaptive sample size determination. Maximal statistical efficiency will be exploited even when dramatic or multiple adaptations are made. Such a trial consists of adaptive determination of sample size at an interim analysis and implementation of frequentist statistical test at the interim and final analysis with a prefixed significance level. The required assumptions for the stage-wise test statistics are independent and stationary increments and normality. Predetermination of adaptation rule is not required. Depends: R (>= 3.5.0) License: GPL (>= 2) Encoding: UTF-8 URL: https://github.com/ca4wa/R-adpss LinkingTo: Rcpp (>= 0.12.17) Imports: Rcpp (>= 0.12.17) RoxygenNote: 7.2.2 Suggests: knitr, rmarkdown VignetteBuilder: knitr Repository: https://ca4wa.r-universe.dev Date/Publication: 2022-11-15 06:16:39 UTC RemoteUrl: https://github.com/ca4wa/r-adpss RemoteRef: HEAD RemoteSha: fa0cb62bd74743cbcc4b750b6e9b168bef0bd11f NeedsCompilation: yes Packaged: 2026-10-03 08:43:39 UTC; root Author: Kosuke Kashiwabara [aut, cre] Maintainer: Kosuke Kashiwabara